Bioavailability and Lag

[Generated automatically as a Tutorial summary]

Inputs

Description

Name:biolag_abs_base
Title:Bioavailability and Lag
Author:Wright Dose Ltd
Abstract:
One compartment model absorption dosing with bioavailability and lag parameters.
Keywords:identifiability; bioavailability; lag; dep_one_cmp_cl
Input Script:biolag_abs_base_tut.pyml
Diagram:

Failed to create compartment diagram

True f[X] values

f[KA] = 0.3
f[CL] = 3
f[V] = 20
f[ANOISE_STD] = 1
f[BIO] = 1
f[LAG] = 0

Starting f[X] values

f[KA] = 0.5
f[CL] = 1
f[V] = 15
f[ANOISE_STD] = 5
f[BIO] = 0.5
f[LAG] = 1

Outputs

Generating and Fitting Summaries

Fitted f[X] values

f[KA] = 1
f[CL] = 1.8773
f[V] = 9.71
f[ANOISE_STD] = 0.89432
f[BIO] = 0.34118
f[LAG] = 8.7977

Plots

Dense comp plots

Alternatively see All dense_comp graph plots

Comparison

True objective value

44.2049919534

Final fitted objective value

38.8628954908

Compare Main f[X]

Name Initial Fitted True Prop. Error Abs. Error
f[KA] 0.5 1 0.3 233.33% 7.00e-01
f[CL] 1 1.88 3 37.42% 1.12e+00
f[V] 15 9.71 20 51.45% 1.03e+01
f[BIO] 0.5 0.341 1 65.88% 6.59e-01
f[LAG] 1 8.8 0 inf 8.80e+00

Compare Noise f[X]

Name Initial Fitted True Prop. Error Abs. Error
f[ANOISE_STD] 5 0.894 1 10.57% 1.06e-01

Compare Variance f[X]

No Variance f[X] values to compare.