Bioavailability and Lag¶
[Generated automatically as a Tutorial summary]
Inputs¶
Description¶
| Name: | biolag_abs_bio |
|---|---|
| Title: | Bioavailability and Lag |
| Author: | Wright Dose Ltd |
| Abstract: |
One compartment model absorption dosing with bioavailability and lag parameters.
| Keywords: | identifiability; bioavailability; lag |
|---|---|
| Input Script: | biolag_abs_bio_tut.pyml |
| Diagram: |
Failed to create compartment diagram
True f[X] values¶
f[KA] = 0.3
f[CL] = 3
f[V] = 20
f[ANOISE_STD] = 1
f[BIO] = 0.583
f[LAG] = 0
Starting f[X] values¶
f[KA] = 0.5
f[CL] = 1
f[V] = 15
f[ANOISE_STD] = 5
f[BIO] = 1
f[LAG] = 1
Outputs¶
Generating and Fitting Summaries¶
- Gen: Bioavailability and Lag (gen)
- Fit: Bioavailability and Lag (fit)
Fitted f[X] values¶
f[KA] = 0.40372
f[CL] = 2.6242
f[V] = 16.151
f[ANOISE_STD] = 0.90054
f[BIO] = 1
f[LAG] = 0.0016458
Plots¶
Comparison¶
True objective value¶
44.2049919535
Final fitted objective value¶
39.6302527647
Compare Main f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[KA] | 0.5 | 0.404 | 0.3 | 34.57% | 1.04e-01 |
| f[CL] | 1 | 2.62 | 3 | 12.53% | 3.76e-01 |
| f[V] | 15 | 16.2 | 20 | 19.25% | 3.85e+00 |
| f[BIO] | 1 | 1 | 0.583 | 71.53% | 4.17e-01 |
| f[LAG] | 1 | 0.00165 | 0 | inf | 1.65e-03 |
Compare Noise f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[ANOISE_STD] | 5 | 0.901 | 1 | 9.95% | 9.95e-02 |
Compare Variance f[X]¶
No Variance f[X] values to compare.