Bioavailability and Lag¶
[Generated automatically as a Fitting summary]
Inputs¶
Description¶
| Name: | biolag_abs_both |
|---|---|
| Title: | Bioavailability and Lag |
| Author: | Wright Dose Ltd |
| Abstract: |
One compartment model absorption dosing with bioavailability and lag parameters.
| Keywords: | identifiability; bioavailability; lag |
|---|---|
| Input Script: | biolag_abs_both_fit.pyml |
| Input Data: | synthetic_data.csv |
| Diagram: |
Initial fixed effect estimates¶
f[KA] = 0.5
f[CL] = 1
f[V] = 15
f[ANOISE_STD] = 5
f[BIO] = 1
f[LAG] = 1
Outputs¶
Final fitted fixed effects¶
f[KA] = 0.97089
f[CL] = 1.6898
f[V] = 13.526
f[ANOISE_STD] = 0.90185
f[BIO] = 1
f[LAG] = 0.00049507
Fitted parameter .csv files¶
| Fixed Effects: | fx_params.csv (fit) |
|---|---|
| Random Effects: | rx_params.csv (fit) |
| Model params: | mx_params.csv (fit) |
| State values: | sx_params.csv (fit) |
| Predictions: | px_params.csv (fit) |
Plots¶
Comparison¶
Compare Main f[X]¶
| Variable Name | Fitted Value | Starting Value | Prop Change | Abs Change |
|---|---|---|---|---|
| f[KA] | 0.970889 | 0.5 | 0.941777 | 0.470889 |
| f[CL] | 1.68982 | 1 | 0.68982 | 0.68982 |
| f[V] | 13.5257 | 15 | 0.0982881 | 1.47432 |
| f[BIO] | 1 | 1 | 0 | 0 |
| f[LAG] | 0.000495075 | 1 | 0.999505 | 0.999505 |
Compare Noise f[X]¶
| Variable Name | Fitted Value | Starting Value | Prop Change | Abs Change |
|---|---|---|---|---|
| f[ANOISE_STD] | 0.901855 | 5 | 0.819629 | 4.09815 |