Bioavailability and Lag¶
[Generated automatically as a Tutorial summary]
Inputs¶
Description¶
| Name: | biolag_abs_both |
|---|---|
| Title: | Bioavailability and Lag |
| Author: | Wright Dose Ltd |
| Abstract: |
One compartment model absorption dosing with bioavailability and lag parameters.
| Keywords: | identifiability; bioavailability; lag |
|---|---|
| Input Script: | biolag_abs_both_tut.pyml |
| Diagram: |
Failed to create compartment diagram
True f[X] values¶
f[KA] = 0.3
f[CL] = 3
f[V] = 20
f[ANOISE_STD] = 1
f[BIO] = 0.583
f[LAG] = 5
Starting f[X] values¶
f[KA] = 0.5
f[CL] = 1
f[V] = 15
f[ANOISE_STD] = 5
f[BIO] = 1
f[LAG] = 1
Outputs¶
Generating and Fitting Summaries¶
- Gen: Bioavailability and Lag (gen)
- Fit: Bioavailability and Lag (fit)
Fitted f[X] values¶
f[KA] = 0.97089
f[CL] = 1.6898
f[V] = 13.526
f[ANOISE_STD] = 0.90185
f[BIO] = 1
f[LAG] = 0.00049507
Plots¶
Comparison¶
True objective value¶
44.2049919535
Final fitted objective value¶
39.6942478038
Compare Main f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[KA] | 0.5 | 0.971 | 0.3 | 223.63% | 6.71e-01 |
| f[CL] | 1 | 1.69 | 3 | 43.67% | 1.31e+00 |
| f[V] | 15 | 13.5 | 20 | 32.37% | 6.47e+00 |
| f[BIO] | 1 | 1 | 0.583 | 71.53% | 4.17e-01 |
| f[LAG] | 1 | 0.000495 | 5 | 99.99% | 5.00e+00 |
Compare Noise f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[ANOISE_STD] | 5 | 0.902 | 1 | 9.81% | 9.81e-02 |
Compare Variance f[X]¶
No Variance f[X] values to compare.