Bioavailability and Lag¶
[Generated automatically as a Tutorial summary]
Inputs¶
Description¶
| Name: | biolag_abs_lag |
|---|---|
| Title: | Bioavailability and Lag |
| Author: | Wright Dose Ltd |
| Abstract: |
One compartment model absorption dosing with bioavailability and lag parameters.
| Keywords: | identifiability; bioavailability; lag; dep_one_cmp_cl |
|---|---|
| Input Script: | biolag_abs_lag_tut.pyml |
| Diagram: |
Failed to create compartment diagram
True f[X] values¶
f[KA] = 0.3
f[CL] = 3
f[V] = 20
f[ANOISE_STD] = 1
f[BIO] = 1
f[LAG] = 5
Starting f[X] values¶
f[KA] = 0.5
f[CL] = 1
f[V] = 15
f[ANOISE_STD] = 5
f[BIO] = 1
f[LAG] = 1
Outputs¶
Generating and Fitting Summaries¶
- Gen: Bioavailability and Lag (gen)
- Fit: Bioavailability and Lag (fit)
Fitted f[X] values¶
f[KA] = 1
f[CL] = 3.2269
f[V] = 22.515
f[ANOISE_STD] = 0.89118
f[BIO] = 1
f[LAG] = 8.6664
Plots¶
Comparison¶
True objective value¶
44.2049919534
Final fitted objective value¶
38.5225391604
Compare Main f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[KA] | 0.5 | 1 | 0.3 | 233.33% | 7.00e-01 |
| f[CL] | 1 | 3.23 | 3 | 7.56% | 2.27e-01 |
| f[V] | 15 | 22.5 | 20 | 12.58% | 2.52e+00 |
| f[BIO] | 1 | 1 | 1 | 0.00% | 0.00e+00 |
| f[LAG] | 1 | 8.67 | 5 | 73.33% | 3.67e+00 |
Compare Noise f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[ANOISE_STD] | 5 | 0.891 | 1 | 10.88% | 1.09e-01 |
Compare Variance f[X]¶
No Variance f[X] values to compare.