Bioavailability and Lag¶
[Generated automatically as a Tutorial summary]
Inputs¶
Description¶
| Name: | biolag_abs_base |
|---|---|
| Title: | Bioavailability and Lag |
| Author: | Wright Dose Ltd |
| Abstract: |
One compartment model absorption dosing with bioavailability and lag parameters.
| Keywords: | identifiability; bioavailability; lag; dep_one_cmp_cl |
|---|---|
| Input Script: | biolag_abs_base_tut.pyml |
| Diagram: |
Failed to create compartment diagram
True f[X] values¶
f[KA] = 0.3
f[CL] = 3
f[V] = 20
f[ANOISE_STD] = 1
f[BIO] = 1
f[LAG] = 0
Starting f[X] values¶
f[KA] = 0.5
f[CL] = 1
f[V] = 15
f[ANOISE_STD] = 5
f[BIO] = 0.5
f[LAG] = 1
Outputs¶
Generating and Fitting Summaries¶
- Gen: Bioavailability and Lag (gen)
- Fit: Bioavailability and Lag (fit)
Fitted f[X] values¶
f[KA] = 1
f[CL] = 1.9103
f[V] = 9.891
f[ANOISE_STD] = 0.89505
f[BIO] = 0.34735
f[LAG] = 8.798
Plots¶
Comparison¶
True objective value¶
44.2049919534
Final fitted objective value¶
38.8629431473
Compare Main f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[KA] | 0.5 | 1 | 0.3 | 233.33% | 7.00e-01 |
| f[CL] | 1 | 1.91 | 3 | 36.32% | 1.09e+00 |
| f[V] | 15 | 9.89 | 20 | 50.55% | 1.01e+01 |
| f[BIO] | 0.5 | 0.347 | 1 | 65.27% | 6.53e-01 |
| f[LAG] | 1 | 8.8 | 0 | inf | 8.80e+00 |
Compare Noise f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[ANOISE_STD] | 5 | 0.895 | 1 | 10.50% | 1.05e-01 |
Compare Variance f[X]¶
No Variance f[X] values to compare.