Bioavailability and Lag¶
[Generated automatically as a Tutorial summary]
Inputs¶
Description¶
| Name: | biolag_abs_base |
|---|---|
| Title: | Bioavailability and Lag |
| Author: | Wright Dose Ltd |
| Abstract: |
One compartment model absorption dosing with bioavailability and lag parameters.
| Keywords: | identifiability; bioavailability; lag; dep_one_cmp_cl |
|---|---|
| Input Script: | biolag_abs_base_tut.pyml |
| Diagram: |
True f[X] values¶
f[KA] = 0.3000
f[CL] = 3.0000
f[V] = 20.0000
f[ANOISE_STD] = 1.0000
f[BIO] = 1.0000
f[LAG] = 0.0000
Starting f[X] values¶
f[KA] = 0.5000
f[CL] = 1.0000
f[V] = 15.0000
f[ANOISE_STD] = 5.0000
f[BIO] = 0.5000
f[LAG] = 1.0000
Outputs¶
Generating and Fitting Summaries¶
- Gen: Bioavailability and Lag (gen)
- Fit: Bioavailability and Lag (fit)
Fitted f[X] values¶
f[KA] = 1.0000
f[CL] = 2.0511
f[V] = 10.6034
f[ANOISE_STD] = 0.8941
f[BIO] = 0.3727
f[LAG] = 8.7974
Plots¶
Comparison¶
True objective value¶
44.2050
Final fitted objective value¶
38.8629
Compare Main f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[KA] | 0.5 | 1 | 0.3 | 233.33% | 7.00e-01 |
| f[CL] | 1 | 2.05 | 3 | 31.63% | 9.49e-01 |
| f[V] | 15 | 10.6 | 20 | 46.98% | 9.40e+00 |
| f[BIO] | 0.5 | 0.373 | 1 | 62.73% | 6.27e-01 |
| f[LAG] | 1 | 8.8 | 0 | inf | 8.80e+00 |
Compare Noise f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[ANOISE_STD] | 5 | 0.894 | 1 | 10.59% | 1.06e-01 |
Compare Variance f[X]¶
No Variance f[X] values to compare.