Bioavailability and Lag

[Generated automatically as a Tutorial summary]

Inputs

Description

Name:biolag_abs_lag
Title:Bioavailability and Lag
Author:Wright Dose Ltd
Abstract:
One compartment model absorption dosing with bioavailability and lag parameters.
Keywords:identifiability; bioavailability; lag; dep_one_cmp_cl
Input Script:biolag_abs_lag_tut.pyml
Diagram:

True f[X] values

f[KA] = 0.3000
f[CL] = 3.0000
f[V] = 20.0000
f[ANOISE_STD] = 1.0000
f[BIO] = 1.0000
f[LAG] = 5.0000

Starting f[X] values

f[KA] = 0.5000
f[CL] = 1.0000
f[V] = 15.0000
f[ANOISE_STD] = 5.0000
f[BIO] = 1.0000
f[LAG] = 1.0000

Outputs

Generating and Fitting Summaries

Fitted f[X] values

f[KA] = 1.0000
f[CL] = 3.2273
f[V] = 22.5113
f[ANOISE_STD] = 0.8915
f[BIO] = 1.0000
f[LAG] = 8.6654

Plots

Dense comp plots

Alternatively see All dense_comp graph plots

Comparison

True objective value

44.2050

Final fitted objective value

38.5225

Compare Main f[X]

Name Initial Fitted True Prop. Error Abs. Error
f[KA] 0.5 1 0.3 233.33% 7.00e-01
f[CL] 1 3.23 3 7.58% 2.27e-01
f[V] 15 22.5 20 12.56% 2.51e+00
f[BIO] 1 1 1 0.00% 0.00e+00
f[LAG] 1 8.67 5 73.31% 3.67e+00

Compare Noise f[X]

Name Initial Fitted True Prop. Error Abs. Error
f[ANOISE_STD] 5 0.892 1 10.85% 1.08e-01

Compare Variance f[X]

No Variance f[X] values to compare.