Bioavailability and Lag¶
[Generated automatically as a Tutorial summary]
Inputs¶
Description¶
| Name: | biolag_abs_base |
|---|---|
| Title: | Bioavailability and Lag |
| Author: | Wright Dose Ltd |
| Abstract: |
One compartment model absorption dosing with bioavailability and lag parameters.
| Keywords: | identifiability; bioavailability; lag; dep_one_cmp_cl |
|---|---|
| Input Script: | biolag_abs_base_tut.pyml |
| Diagram: |
True f[X] values¶
f[KA] = 0.3000
f[CL] = 3.0000
f[V] = 20.0000
f[ANOISE_STD] = 1.0000
f[BIO] = 1.0000
f[LAG] = 0.0000
Starting f[X] values¶
f[KA] = 0.5000
f[CL] = 1.0000
f[V] = 15.0000
f[ANOISE_STD] = 5.0000
f[BIO] = 0.5000
f[LAG] = 1.0000
Outputs¶
Generating and Fitting Summaries¶
- Gen: Bioavailability and Lag (gen)
- Fit: Bioavailability and Lag (fit)
Fitted f[X] values¶
f[KA] = 1.0000
f[CL] = 2.0220
f[V] = 10.4802
f[ANOISE_STD] = 0.8945
f[BIO] = 0.3681
f[LAG] = 8.7948
Plots¶
Comparison¶
True objective value¶
44.2050
Final fitted objective value¶
38.8669
Compare Main f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[KA] | 0.5 | 1 | 0.3 | 233.33% | 7.00e-01 |
| f[CL] | 1 | 2.02 | 3 | 32.60% | 9.78e-01 |
| f[V] | 15 | 10.5 | 20 | 47.60% | 9.52e+00 |
| f[BIO] | 0.5 | 0.368 | 1 | 63.19% | 6.32e-01 |
| f[LAG] | 1 | 8.79 | 0 | inf | 8.79e+00 |
Compare Noise f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[ANOISE_STD] | 5 | 0.894 | 1 | 10.55% | 1.06e-01 |
Compare Variance f[X]¶
No Variance f[X] values to compare.