Bioavailability and Lag¶
[Generated automatically as a Tutorial summary]
Inputs¶
Description¶
| Name: | biolag_abs_both |
|---|---|
| Title: | Bioavailability and Lag |
| Author: | Wright Dose Ltd |
| Abstract: |
One compartment model absorption dosing with bioavailability and lag parameters.
| Keywords: | identifiability; bioavailability; lag |
|---|---|
| Input Script: | biolag_abs_both_tut.pyml |
| Diagram: |
Failed to create compartment diagram
True f[X] values¶
f[KA] = 0.3000
f[CL] = 3.0000
f[V] = 20.0000
f[ANOISE_STD] = 1.0000
f[BIO] = 0.5830
f[LAG] = 5.0000
Starting f[X] values¶
f[KA] = 0.5000
f[CL] = 1.0000
f[V] = 15.0000
f[ANOISE_STD] = 5.0000
f[BIO] = 0.8000
f[LAG] = 1.0000
Outputs¶
Generating and Fitting Summaries¶
- Gen: Bioavailability and Lag (gen)
- Fit: Bioavailability and Lag (fit)
Fitted f[X] values¶
f[KA] = 0.9899
f[CL] = 2.5346
f[V] = 15.4897
f[ANOISE_STD] = 0.8940
f[BIO] = 0.4852
f[LAG] = 8.8987
Plots¶
Comparison¶
True objective value¶
44.2050
Final fitted objective value¶
38.7660
Compare Main f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[KA] | 0.5 | 0.99 | 0.3 | 229.97% | 6.90e-01 |
| f[CL] | 1 | 2.53 | 3 | 15.51% | 4.65e-01 |
| f[V] | 15 | 15.5 | 20 | 22.55% | 4.51e+00 |
| f[BIO] | 0.8 | 0.485 | 0.583 | 16.78% | 9.78e-02 |
| f[LAG] | 1 | 8.9 | 5 | 77.97% | 3.90e+00 |
Compare Noise f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[ANOISE_STD] | 5 | 0.894 | 1 | 10.60% | 1.06e-01 |
Compare Variance f[X]¶
No Variance f[X] values to compare.