Bioavailability and Lag¶
[Generated automatically as a Tutorial summary]
Inputs¶
Description¶
| Name: | biolag_abs_lag |
|---|---|
| Title: | Bioavailability and Lag |
| Author: | Wright Dose Ltd |
| Abstract: |
One compartment model absorption dosing with bioavailability and lag parameters.
| Keywords: | identifiability; bioavailability; lag; dep_one_cmp_cl |
|---|---|
| Input Script: | biolag_abs_lag_tut.pyml |
| Diagram: |
Failed to create compartment diagram
True f[X] values¶
f[KA] = 0.3000
f[CL] = 3.0000
f[V] = 20.0000
f[ANOISE_STD] = 1.0000
f[BIO] = 1.0000
f[LAG] = 5.0000
Starting f[X] values¶
f[KA] = 0.5000
f[CL] = 1.0000
f[V] = 15.0000
f[ANOISE_STD] = 5.0000
f[BIO] = 0.8000
f[LAG] = 1.0000
Outputs¶
Generating and Fitting Summaries¶
- Gen: Bioavailability and Lag (gen)
- Fit: Bioavailability and Lag (fit)
Fitted f[X] values¶
f[KA] = 0.9911
f[CL] = 0.8428
f[V] = 5.9136
f[ANOISE_STD] = 0.8909
f[BIO] = 0.2622
f[LAG] = 8.6494
Plots¶
Comparison¶
True objective value¶
44.2050
Final fitted objective value¶
38.5365
Compare Main f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[KA] | 0.5 | 0.991 | 0.3 | 230.38% | 6.91e-01 |
| f[CL] | 1 | 0.843 | 3 | 71.91% | 2.16e+00 |
| f[V] | 15 | 5.91 | 20 | 70.43% | 1.41e+01 |
| f[BIO] | 0.8 | 0.262 | 1 | 73.78% | 7.38e-01 |
| f[LAG] | 1 | 8.65 | 5 | 72.99% | 3.65e+00 |
Compare Noise f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[ANOISE_STD] | 5 | 0.891 | 1 | 10.91% | 1.09e-01 |
Compare Variance f[X]¶
No Variance f[X] values to compare.